scHelix: Asymmetric Dual-Stream Integration via Explicit Gene-Level Disentanglement

A critical challenge in single-cell RNA sequencing (scRNA-seq) integration is resolving the tension between eliminating batch effects and maintaining biological fidelity. While recent evidence indicates that batch effects manifest heterogeneously across genes, most existing methods process the transcriptome uniformly, frequently resulting in over-correction and loss of subtle biological signals. To address this, we present scHelix, a dataset-adaptive framework that fundamentally changes how features are processed by explicitly partitioning genes into domain-invariant Anchors and domain-sensitive Variants at the input level. scHelix utilizes a dual-stream sparse diffusion encoder equipped with stop-gradient graph caching to efficiently learn multi-scale structural representations. The core of our approach is a novel asymmetric Align-Refine-Fuse protocol: the unstable Variant stream is first aligned to the robust topology of the Anchor stream, followed by a conservative refinement phase where the Anchor stream absorbs denoised details via bounded residual gating. This divide-and-conquer architecture prevents shortcut learning and ensures robust batch removal without compromising the integrity of biological clusters. Extensive benchmarking demonstrates that scHelix outperforms state-of-the-art methods.

Reduce the Artifacts Bias for More Generalizable AI-Generated Image Detection

As the misuse of AI-generated images grows, generalizable image detection techniques are urgently needed. Recent state-of-the-art (SOTA) methods adopt aligned training datasets to reduce content, size, and format biases, empowering models to capture robust forgery cues. A common strategy is to employ reconstruction techniques, e.g., VAE and DDIM, which show remarkable results in diffusion-based methods. However, such reconstruction-based approaches typically introduce limited and homogeneous artifacts, which cannot fully capture diverse generative patterns, such as GAN-based methods. To complement reconstruction-based fake images with aligned yet diverse artifact patterns, we propose a GAN-based upsampling approach that mimics GAN-generated fake patterns while preserving content, size, and format alignment. This naturally results in two aligned but distinct types of fake images. However, due to the domain shift between reconstruction-based and upsampling-based fake images, direct mixed training causes suboptimal results, where one domain disrupts feature learning of the other. Accordingly, we propose a Separate Expert Fusion (SEF) framework to extract complementary artifact information and reduce inter-domain interference. We first train domain-specific experts via LoRA adaptation on a frozen foundational model, then conduct decoupled fusion with a gating network to adaptively combine expert features while retaining their specialized knowledge. Rather than merely benefiting GAN-generated image detection, this design introduces diverse and complementary artifact patterns that enable SEF to learn a more robust decision boundary and improve generalization across broader generative methods. Extensive experiments demonstrate that our method yields strong results across 13 diverse benchmarks. Codes are released at: https://github.com/liyih/SEF_AIGC_detection.

Adaptive 3D Convolution for Remote Sensing Image Fusion

Remote sensing image fusion aims to create a high-resolution multi/hyper-spectral image from a high-resolution image with limited spectral information and a low-resolution image with abundant spectral data. Recently, deep learning (DL) techniques have shown significant effectiveness in this area. Most DL-based methods approach image fusion as a 2D problem by encoding spectral information into feature map channels. However, our research suggests that this strategy introduces notable spectral distortions. In contrast, some methods consider spectral data as an additional dimension, utilizing standard 3D convolutions to preserve spectral information. Nevertheless, in a standard 3D convolutional layer, the same set of kernels is applied across all input regions, which we have found to be sub-optimal for image fusion. Furthermore, standard 3D convolutions necessitate substantial computational resources. To address these challenges, we propose a novel convolutional paradigm called Adaptive 3D Convolution (Ada3D) for remote sensing image fusion. Ada3D applies a unique set of 3D kernels to each input voxel, enabling the capture of fine-grained details. These adaptive kernels are generated through a two-step process: (i) spatial and spectral kernels are derived from their respective image sources; (ii) these two types of kernels are then combined to form content-aware 3D kernels that effectively integrate spatial and spectral information. Additionally, adaptive biases are introduced to enhance the convolutional outcome at the voxel level. Furthermore, we incorporate the group convolution technique to reduce computational complexity. As a result, Ada3D offers full adaptivity in an efficient manner. Evaluation results across five datasets demonstrate that our method achieves SOTA performance, underscoring the superiority of Ada3D. The code is available at https://github.com/PSRben/Ada3D.

Reward-Guided Semantic Evolution for Test-time Adaptive Object Detection

Open-vocabulary object detection with vision-language models (VLMs) such as Grounding DINO suffers from performance degradation under test-time distribution shifts, primarily due to semantic misalignment between text embeddings and shifted visual embeddings of region proposals. While recent test-time adaptive object detection methods for VLM-based either rely on costly backpropagation or bypass semantic misalignment via external memory, none directly and efficiently align text and vision in a training-free manner. To address this, we propose Reward-Guided Semantic Evolution (RGSE), a training-free framework that directly refines the text embeddings at test time. Inspired by evolutionary search, RGSE treats text embedding adaptation as a semantic search process: it perturbs text embeddings as candidate variants, evaluates them via cosine similarity with current and historical high-confidence visual proposals as a reward signal, and fuses them into a refined embedding through reward-weighted averaging. Without any backpropagation, RGSE achieves state-of-the-art performance across multiple detection benchmarks while adding minimal computational overhead. Our code will be open source upon publication.

TurboTalk: Progressive Distillation for One-Step Audio-Driven Talking Avatar Generation

Existing audio-driven video digital human generation models rely on multi-step denoising, resulting in substantial computational overhead that severely limits their deployment in real-world settings. While one-step distillation approaches can significantly accelerate inference, they often suffer from training instability. To address this challenge, we propose TurboTalk, a two-stage progressive distillation framework that effectively compresses a multi-step audio-driven video diffusion model into a single-step generator. We first adopt Distribution Matching Distillation to obtain a strong and stable 4-step student, and then progressively reduce the denoising steps from 4 to 1 through adversarial distillation. To ensure stable training under extreme step reduction, we introduce a progressive timestep sampling strategy and a self-compare adversarial objective that provides an intermediate adversarial reference that stabilizes progressive distillation. Our method achieve single-step generation of video talking avatar, boosting inference speed by 120 times while maintaining high generation quality.

Direct Discrepancy Replay: Distribution-Discrepancy Condensation and Manifold-Consistent Replay for Continual Face Forgery Detection

Continual face forgery detection (CFFD) requires detectors to learn emerging forgery paradigms without forgetting previously seen manipulations. Existing CFFD methods commonly rely on replaying a small amount of past data to mitigate forgetting. Such replay is typically implemented either by storing a few historical samples or by synthesizing pseudo-forgeries from detector-dependent perturbations. Under strict memory budgets, the former cannot adequately cover diverse forgery cues and may expose facial identities, while the latter remains strongly tied to past decision boundaries. We argue that the core role of replay in CFFD is to reinstate the distributions of previous forgery tasks during subsequent training. To this end, we directly condense the discrepancy between real and fake distributions and leverage real faces from the current stage to perform distribution-level replay. Specifically, we introduce Distribution-Discrepancy Condensation (DDC), which models the real-to-fake discrepancy via a surrogate factorization in characteristic-function space and condenses it into a tiny bank of distribution discrepancy maps. We further propose Manifold-Consistent Replay (MCR), which synthesizes replay samples through variance-preserving composition of these maps with current-stage real faces, yielding samples that reflect previous-task forgery cues while remaining compatible with current real-face statistics. Operating under an extremely small memory budget and without directly storing raw historical face images, our framework consistently outperforms prior CFFD baselines and significantly mitigates catastrophic forgetting. Replay-level privacy analysis further suggests reduced identity leakage risk relative to selection-based replay.

MAT-Cell: A Multi-Agent Tree-Structured Reasoning Framework for Batch-Level Single-Cell Annotation

Automated cellular reasoning faces a core dichotomy: supervised methods fall into the Reference Trap and fail to generalize to out-of-distribution cell states, while large language models (LLMs), without grounded biological priors, suffer from a Signal-to-Noise Paradox that produces spurious associations. We propose MAT-Cell, a neuro-symbolic reasoning framework that reframes single-cell analysis from black-box classification into constructive, verifiable proof generation. MAT-Cell injects symbolic constraints through adaptive Retrieval-Augmented Generation (RAG) to ground neural reasoning in biological axioms and reduce transcriptomic noise. It further employs a dialectic verification process with homogeneous rebuttal agents to audit and prune reasoning paths, forming syllogistic derivation trees that enforce logical consistency.Across large-scale and cross-species benchmarks, MAT-Cell significantly outperforms state-of-the-art (SOTA) models and maintains robust per-formance in challenging scenarios where baselinemethods severely degrade. Code is available at https://gith ub.com/jiangliu91/MAT-Cell-A-Mul ti-Agent-Tree-Structured-Reasoni ng-Framework-for-Batch-Level-Sin gle-Cell-Annotation.

UniDA3D: A Unified Domain-Adaptive Framework for Multi-View 3D Object Detection

Camera-only 3D object detection is critical for autonomous driving, offering a cost-effective alternative to LiDAR based methods. In particular, multi-view 3D object detection has emerged as a promising direction due to its balanced trade-off between performance and cost. However, existing methods often suffer significant performance degradation under complex environmental conditions such as nighttime, fog, and rain, primarily due to their reliance on training data collected mostly in ideal conditions. To address this challenge, we propose UniDA3D, a unified domain-adaptive multi-view 3D object detector designed for robust perception under diverse adverse conditions. UniDA3D formulates nighttime, rainy, and foggy scenes as a unified multi target domain adaptation problem and leverages a novel query guided domain discrepancy mitigation (QDDM) module to align object features between source and target domains at both batch and global levels via query-centric adversarial and contrastive learning. Furthermore, we introduce a domain-adaptive teacher student training pipeline with an exponential-moving-average teacher and dynamically updated high-quality pseudo labels to enhance consistency learning and suppress background noise in unlabeled target domains. In contrast to prior approaches that require separate training for each condition, UniDA3D performs a single unified training process across multiple domains, enabling robust all-weather 3D perception. On a synthesized multi-view 3D benchmark constructed by generating nighttime, rainy, and foggy counterparts from nuScenes (nuScenes-Night, nuScenes-Rain, and nuScenes-Haze), UniDA3D consistently outperforms state of-the-art camera-only multi-view 3D detectors under extreme conditions, achieving substantial gains in mAP and NDS while maintaining real-time inference efficiency.

CTForensics: A Comprehensive Dataset and Method for AI-Generated CT Image Detection

With the rapid development of generative AI in medical imaging, synthetic Computed Tomography (CT) images have demonstrated great potential in applications such as data augmentation and clinical diagnosis, but they also introduce serious security risks. Despite the increasing security concerns, existing studies on CT forgery detection are still limited and fail to adequately address real-world challenges. These limitations are mainly reflected in two aspects: the absence of datasets that can effectively evaluate model generalization to reflect the real-world application requirements, and the reliance on detection methods designed for natural images that are insensitive to CT-specific forgery artifacts. In this view, we propose CTForensics, a comprehensive dataset designed to systematically evaluate the generalization capability of CT forgery detection methods, which includes ten diverse CT generative methods. Moreover, we introduce the Enhanced Spatial-Frequency CT Forgery Detector (ESF-CTFD), an efficient CNN-based neural network that captures forgery cues across the wavelet, spatial, and frequency domains. First, it transforms the input CT image into three scales and extracts features at each scale via the Wavelet-Enhanced Central Stem. Then, starting from the largest-scale features, the Spatial Process Block gradually performs feature fusion with the smaller-scale ones. Finally, the Frequency Process Block learns frequency-domain information for predicting the final results. Experiments demonstrate that ESF-CTFD consistently outperforms existing methods and exhibits superior generalization across different CT generative models.

From Intuition to Investigation: A Tool-Augmented Reasoning MLLM Framework for Generalizable Face Anti-Spoofing

Face recognition remains vulnerable to presentation attacks, calling for robust Face Anti-Spoofing (FAS) solutions. Recent MLLM-based FAS methods reformulate the binary classification task as the generation of brief textual descriptions to improve cross-domain generalization. However, their generalizability is still limited, as such descriptions mainly capture intuitive semantic cues (e.g., mask contours) while struggling to perceive fine-grained visual patterns. To address this limitation, we incorporate external visual tools into MLLMs to encourage deeper investigation of subtle spoof clues. Specifically, we propose the Tool-Augmented Reasoning FAS (TAR-FAS) framework, which reformulates the FAS task as a Chain-of-Thought with Visual Tools (CoT-VT) paradigm, allowing MLLMs to begin with intuitive observations and adaptively invoke external visual tools for fine-grained investigation. To this end, we design a tool-augmented data annotation pipeline and construct the ToolFAS-16K dataset, which contains multi-turn tool-use reasoning trajectories. Furthermore, we introduce a tool-aware FAS training pipeline, where Diverse-Tool Group Relative Policy Optimization (DT-GRPO) enables the model to autonomously learn efficient tool use. Extensive experiments under a challenging one-to-eleven cross-domain protocol demonstrate that TAR-FAS achieves SOTA performance while providing fine-grained visual investigation for trustworthy spoof detection.